Synthesis and surface activity of some imidazole, 1,2,4-triazole, and tetrazole derivatives
Imidazole, 1,2,4-triazole, and tetrazole derivatives containing large alkyl substituents are prepared, and their surface activity is studied.
Abramzon,Pevzner,Kofman,Alam
p. 1841 - 1848
(2007/10/03)
Tetrazoles. XXXI. Phase-Transfer Reactions of 1-Substituted Tetrazole-5-thiones and Their Derivatives
Alkylation of 1-substituted tetrazole-5-thiones under conditions of phase-transfer catalysis in the two-phase system liquid-liquid proceeds regioselectively at the sulfur atom, regardless of the alkylating agent and phase-transfer catalyst. Phase-transfer oxidation of the 5-alkylthiotetrazoles thus obtained by potassium permanganate is a convenient method for preparation of 5-alkylsulfonyltetrazoles which can be used to synthesize functionally substituted tetrazoles.
Gol'tsberg,Koldobskii
p. 1194 - 1201
(2007/10/03)
Tetrazoles. XXXII. Reactions of 1-R-Tetrazole-5-Thiones and Their Derivatives under Conditions of Phase Transfer Catalysis. Selection of Phase Transfer Catalyst
Among the six investigated catalysts of phase transfer the most effective at alkylation of 1-phenyltetrazole-5-thione and oxidation of 5-methylthio-phenyltetrazole turned out to be the benzyldimetyhyl(5-methoxycarbonylpentyl)ammonium bromide. The directio
A synthesis of (1-phenyltetrazol-5-ylthio)acetic acid derivatives has been developed.Functional variations concern the carboxylic group and/or the 4 position of phenyl group.Most of the compounds prepared have been tested with regard to their antimycobact