Synthese der Pestwurzinhaltsstoffe (+)-Petasin und (+)-Isopetasin
The first total synthesis of optically active petasine 1 and isopetasine 2 succeeded by applying an annelation reaction, based on the reaction of cyclic δ-ketocarboxylic acids with N-phenyliminoketenylidenetriphenylphosphorane. 1 and 2 are biologically ac
Witschel, Matthias Christian,Bestmann, Hans Juergen