cas 474334-89-9, 1-(3-CARBOMETHOXYPHENYL)-4-METHYLPIPERA& | Articles data ｜lookchem

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474334-89-9

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SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS
Benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethyfase, including LSD1 and LSD2; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1 and/or LSD2.
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Paragraph 00194

(2017/01/23)

OXABOROLE ESTERS AND USES THEREOF
The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
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Page/Page column 63

(2017/12/05)

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Chemical Properties

Boiling Point: 169-172 °C/0.9 mmHg(lit.)
Flash Point:110 °C
Density: 1.119 g/mL at 25 °C(lit.)
Vapor Pressure: 1.94E-05mmHg at 25°C
Refractive Index: n20/D 1.563(lit.)
PKA: 7.67±0.42(Predicted)
PSA: 32.78000
LogP: 1.22790

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