The synthesis of a series of 3-aryl pyrazolo[4,3-d]pyrimidines as potential corticotropin-releasing factor (CRF-1) antagonists is described. The effects of substitution on the aromatic ring, the amino group and the pyrazolo ring on CRF-1 receptor binding
Yuan, Jun,Gulianello, Michael,De Lombaert, Stephane,Brodbeck, Robbin,Kieltyka, Andrzej,Hodgetts, Kevin J
p. 2133 - 2136
(2007/10/03)
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