- Facile syntheses of (-)-montagnetol and (-)-erythrin
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A novel synthetic method is introduced to prepare the biologically important montagnetol and erythrin compounds starting from a 1,3-benzodioxin-4-one, synthesized from commercially available orsellinic acid and erythritol.
- Kumbaraci, Volkan,Gunduz, Hande,Karadeniz, Meric
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p. 6328 - 6330
(2013/11/06)
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- Studies on the resorcylates: biomimetic total syntheses of (+)-montagnetol and (+)-erythrin
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6-(2,4-Dioxopentyl)-2,2-trimethyl-4H-1,3-dioxin-4-one on reflux in toluene gave MeCOCH2COCH2COCH{double bond, long}C{double bond, long}O, which cyclized to 6-(2-oxopropyl)-4-hydroxy-2H-pyran-2-one or was trapped with alcohols to produce resorcylate esters. The method was used for the synthesis of both enantiomers of montagnetol and erythrin.
- Basset, Jean-Fran?ois,Leslie, Colin,Hamprecht, Dieter,White, Andrew J.P.,Barrett, Anthony G.M.
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supporting information; experimental part
p. 783 - 785
(2010/03/24)
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