Enaminones in heterocyclic synthesis: A novel route to polyfunctionalized substituted thiophene, 2,3-dihydro-1,3,4-thiadiazole and naphtho[1,2-b] furan derivatives
The enaminones 1a,b reacted with phenylisothiocyanate to afford the thioanilides 2a,b. The latter could be utilized to synthesize several new polysubstituted thiophenes 9a-f, and 1,3,4-thiadiazoles 12a-f.
Kandeel, Zaghloul E.,Al-Zaydi, Khadija M.,Hafez, Ebtisam A.,Elnagdi, Mohamed H.