Thiourea-based gemfibrozil analogues as HDL-elevating agents.
A series of gemfibrozil analogues with a thiourea moiety embedded in the side chain was prepared and evaluated as HDL-elevating agents. Derivatives 8b, 9b, 9c, and 9d were found to be approximately as effective as gemfibrozil (1) for HDL cholesterol eleva
Coppola, Gary M,Damon, Robert E,Eskesen, J Bruce,France, Dennis S,Paterniti Jr., James R
p. 2439 - 2442
(2007/10/03)
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