New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities
Among the different classes of antibiotics, oxazolidinone derivatives represent important drugs, since their unique mechanism of action overcomes commonly diffused multidrug-resistant bacteria. Anyway, the structural similarity of these molecules to monoa
Identification of phenylisoxazolines as novel and viable antibacterial agents active against gram-positive pathogens
A new and promising group of antibacterial agents, collectively known as the oxazolidinones and exemplified by linezolid (PNU-100766, marketed as Zyvox), have recently emerged as important new therapeutic agents for the treatment of infections caused by G
Barbachyn, Michael R.,Cleek, Gary J.,Dolak, Lester A.,Garmon, Stuart A.,Morris, Joel,Seest, Eric P.,Thomas, Richard C.,Toops, Dana S.,Watt, William,Wishka, Donn G.,Ford, Charles W.,Zurenko, Gary E.,Hamel, Judith C.,Schaadt, Ronda D.,Stapert, Douglas,Yagi, Betty H.,Adams, Wade J.,Friis, Janice M.,Slatter, J. Gregory,Sams, James P.,Oien, Nancee L.,Zaya, Matthew J.,Wienkers, Larry C.,Wynalda, Michael A.
p. 284 - 302
(2007/10/03)
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