Synthesis of a novel dimeric bis-benzimidazole with site-selective DNA-binding properties
We describe the synthesis of bis(3-{4-[2′-(4-methoxyphenyl)-3H,3′H-[5,5′] bibenzimidazolyl-2-yl]phenoxy}propyl)methylamine 8, which has high affinity for the oligonucleotide sequence [A.T]4-[G.C]-[A.T]4.