- SYNTHESIS OF ANALOGUES OF NATURAL PRECOCENES CONTAINING A 8-METHYL SUBSTITUENT
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The synthesis of benzopyran compounds (VIIIa-q), analogues of precocene I (I) substituted on C-8 in the aromatic ring with a methyl group, is described.
- Timar, Tibor,Hosztafi, Sandor,Jaszberenyi, J. Csaba
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p. 617 - 630
(2007/10/02)
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- Pyranochromone derivatives and therapeutic composition comprising same for treatment of allergic diseases
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Novel pyranochromone derivatives having the general formula: STR1 wherein R1 represents hydrogen atom, an alkali metal or an alkyl group containing 1-4 carbon atoms; R2, R3 and R4 represent hydrogen atom or an alkyl group containing 1-4 carbon atoms respectively, provided that both R3 and R4 are not hydrogen atom at the same time; R5 and R6 represent an alkyl group containing 1-4 carbon atoms respectively; and R7 represents hydrogen atom, hydroxyl group, an alkyl group containing 1-4 carbon atoms or an alkoxyl group containing 1-4 carbon atoms. The novel medicaments comprising predominantly the above derivative are effective for the treatment of allergic diseases.
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