- Synthesis method of oxyfluorfen
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The invention discloses a synthesis method of oxyfluorfen. The method comprises the following steps: using 3, 4-dichlorobenzotrifluoride and 2, 4-difluoronitrobenzene as initial raw materials, carrying out etherification reaction to obtain a nitro compound, and carrying out alcoholysis reaction on the nitro compound and a potassium hydroxide ethanol solution to synthesize the oxyfluorfen. According to the method, the 3, 4-dichlorobenzotrifluoride and the 2, 4-difluoronitrobenzene are taken as the initial raw materials, the 3, 4-dichlorobenzotrifluoride and the 2, 4-difluoronitrobenzene are synthesized through etherification and alcoholysis reactions, no isomer is generated, recrystallization is not needed, the content of the synthesized product is greater than 97%, and the yield is greaterthan 93%.
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Page/Page column 4-6
(2020/12/30)
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- Synthesis method of oxyfluorfen
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The invention relates to a synthesis method of oxyfluorfen, which comprises the following steps: (1) reacting 3,4-dichlorobenzotrifluoride, potassium hydroxide and tert-butyl alcohol in a molar ratioof (1-1.5): (3-5): (2-4), dechlorinating in a polar solvent to obtain a mixed solution containing 2-chloro-4-trifluoromethylphenol potassium, cooling, carrying out suction filtration, and carrying outreduced pressure treatment on the mixed solution; (2) adding potassium carbonate to the mixed solution, adding dropwise 2,4-dihalogenated nitrobenzene while heating is performed, with the molar ratioof the potassium carbonate, the 2,4-dihalogenated nitrobenzene and the 3,4-dichlorobenzotrifluoride being (1-1.5): 1: (2-2.3), performing suction filtration after a heat preservation reaction, and adding methylbenzene to dissolve 2,4-bis(2-chloro-4-trifluoromethyl) phenoxy nitrobenzene in the filtrate; and (3) heating the mixed solution to 30 DEG C, then dropwise adding potassium ethylate into the solution, carrying out a heat preservation reaction, with the molar ratio of ethanol, potassium hydroxide and the 2,4-dihalogenated nitrobenzene being 4-5:1.2-1.4:1, and extracting oxyfluorfen fromthe reacted mixed solution. According to the present invention, with the new synthesis method, the synthesis cost of oxyfluorfen is significantly reduced.
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Paragraph 0024; 0043-0056
(2020/08/09)
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- Herbicidal 4-trifluoromethyl-3'-oxygen-substituted-4'-substituted diphenyl ethers
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The herbicidal 4-trifluoromethyl-3'-oxygen-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.
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- Herbicidal 4-trifluoromethyl-3'-nitrogen-substituted-4'-substituted diphenyl ethers
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The herbicidal 4-trifluoromethyl-3'-nitrogen-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.
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- Herbicidal 4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers
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The herbicidal-4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.
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- Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers
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Salts of compounds of the formula STR1 wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, and Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and compositions containing these salts exhibit herbicidal activity.
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- Herbicidal 4-trifluoromethyl 4-nitrodiphenyl ethers
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Compounds of the formula STR1 wherein X is a cyano group, Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and Z is a substituted alkoxy group, and compositions containing these compounds exhibit herbicidal activity.
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- Herbicidal 4-perfluoroacetyl-, 4-perfluoromethylthio-, 4-perfluoromethylsulfinyl-, and 4-perfluoromethylsulfonyl-4'-nitrodiphenyl ethers
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The 4-perfluoroacetyl-, 4-perfluoromethylthio-, 4-perfluoromethylsulfinyl-, and 4-perfluoromethylsulfonyl-4'-nitrodiphenyl ethers comprise a class of compounds that are highly effective herbicides.
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- Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers
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Compounds of the formula STR1 wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and Z is a substituted alkoxy group, And compositions containing these compounds exhibit herbicidal activity.
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- Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers
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Salts of compounds of the formula STR1 wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, and Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, And compositions containing these salts exhibit herbicidal activity.
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