- METHOD FOR THE PRODUCTION OF PRIMARY LONG-CHAIN ALCOHOLS
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The invention relates to a method for the production of linear long-chain alcohols with 20 to 40 carbon atoms by means of a growth reaction with ethylene on aluminium compounds.
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Page/Page column 11-12
(2010/02/15)
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- PROCESS FOR THE PREPARATION OF ALIPHATIC PRIMARY ALCOHOLS AND RELATED INTERMEDIATES IN SUCH PROCESS
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The invention relates to protected alcohol with formula (R1 - O-)mPG, wherein R1 represents a linear, straight-chain alkyl group having 26-30 C-atoms, m is 1 or 2, and PG, forming an ether group in combination with the -O- of the former primary alcohol, represents a protecting group chosen from the group of substituted methyl, substituted ethyl, substituted benzyl and (substituted) silyl groups with at least one substituent on the Si-atom being not a methyl group, in case m = 1; and a diol protecting group in case m = 2, with the proviso that PG is no saccharide. The invention further relates to process for the preparation of such protected alcohols via an organometallic cross coupling reaction.
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Page/Page column 8
(2010/02/11)
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- Synthesis of even C24-C30 primary normal aliphatic alcohols from cyclododecanone
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A simple method has been developed for the oxidation of cyclododecanone by sodium persulfate in an aqueous methanol solution of sulfuric acid to give 12-hydroxydodecanoic acid, which upon treatment with HBr in acetic acid gives 12-bromododecanoic acid with RMgX, where R=C12H25, C14H29, C16H33, and C18H37 in THF in the presence of Li2CuCl4 and subsequent reduction of the salts of the alkanecarboxylic acids by LiAlH4 give primary even normal C24-C30 alcohols.
- Zakharkin, L. I.,Churilova, I. M.,Anikina, E. V.
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- A New Synthesis of Long Chain Acid Esters and Carbinols
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A versatile synthesis of difficulty accessible long chain acid esters and carbinols is described.The synthesis involves acylations at 2- and 5-positions of thiophene.Thioketalation of the resulting ketoesters followed by Raney nickel desulfurization yield acid esters which on LAH reduction give the corresponding carbinols.
- Rao, S. Jagadishwar,Bhalerao, U. T.,Tilak, B. D.
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p. 208 - 211
(2007/10/02)
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