- Fine tuning of receptor polarity for the development of selective naked eye anion receptor
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We designed and synthesized new anion receptors 1, 2, and 3, which have different N-H polarity. According to their N-H polarities, these receptors showed different selectivities for the anions they were interacting with. The difference of selectivity coul
- Park, Jin Joo,Kim, Young-Hee,Kim, Cheal,Kang, Jongmin
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experimental part
p. 3361 - 3366
(2011/06/28)
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- Synthesis of N,N′-diarylalkanediamides and their antimycobacterial and antialgal activity
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A set of N,N′-diarylalkanediamides was synthesized. The compounds were tested for their antimycobacterial and antialgal activity. The antimycobacterial activity of N,N′-diarylalkanediamides depends on the lipophilicity of the respective acid. Antimycobacteri-ally active substances were found only in the series of N,N′-diarylethanediamides and N,N′-diarylbutanediamides. Other compounds (derivatives of pentane-, hexane-, octane- and nonanediamide) were inactive against various strains of mycobacteria. The compounds inhibited growth and chlorophyll production in Chlorella vulgaris. Their relatively low antial-gal activity is probably connected with their lowered aqueous solubility, and hence by a restricted passage of the inhibitor through the hydrophilic regions of thylakoid membranes.
- Kubicova, Lenka,Waisser, Karel,Kunes, Jiri,Kralova, Katarina,Odlerova, Zelmira,Slosarek, Milan,Janota, Jiri,Svoboda, Zbynek
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p. 714 - 726
(2007/10/03)
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- Heterocycles from Heterocycles. 1,3-Diaryl-4,5-imidazolidinediones from 1,3,5-Triarylhexahydro-1,3,5-triazines and Oxalyl Chloride
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1,3-Diaryl-4,5-imidazolidinediones (6) are easily synthesized from 1,3,5-triarylhexahydro-1,3,5-triazines (1) and oxalyl chloride (5) in a reaction not likely to involve the zwitterionic intermediate (3) of the N-methylenearylamine dimer, but viewing the sequential pick up of two units of the monomer (2) by oxalyl chloride (5).The essential role of ethyl alcohol added to the reaction mixture is recognized.Reaction conditions have been optimized and some ten imidazolidinediones (6) were prepared in good to excellent yields.Geometric parameters of 6 were obtained by X-ray diffraction analysis: all the nuclei are found almost in one plane except for a small twist of the phenyl rings about the C-N bond.
- Verardo, Giancarlo,Giumanini, Angelo G.,Gorassini, Fausto,Tolazzi, Marilena,Strazzolini, Paolo
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p. 10609 - 10628
(2007/10/02)
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