Three convergent routes to thiophenes are described, hinging on the radical addition of α-xanthyl ketones to ethyl vinyl sulfide or to vinyl pivalate. The latter route ultimately proved to be the most versatile and efficient (61-94%).
Jullien, Helene,Quiclet-Sire, Beatrice,Tetart, Thomas,Zard, Samir Z.
supporting information
p. 302 - 305
(2014/01/23)
Method of preparing benzazepines and derivatives thereof
The invention relates to a method of preparing benzazepine compounds having general formula (IA) consisting in reacting at least one compound having general formula (IIA) with an olefin, the compound thus obtained then being cyclised such as to produce tetralone, followed by the oxime derivative of same, which, by transformation by a Beckmann rearrangement, gives rise to the desired compounds.
-
Page/Page column 8
(2008/06/13)
Radicals from aldehydes: A convergent access to dienes and δ-lactones
A convenient method for the generation of O,S-acetal xanthates from aldehydes has been developed. The corresponding nucleophilic radicals undergo facile addition to unactivated olefins and the resulting adducts can be further elaborated to generate dienes
Bagal, Sharanjeet K.,Tournier, Lucie,Zard, Samir Z.
p. 1485 - 1490
(2007/10/03)
Synthesis of substituted naphthalenes from α-tetralones generated by a xanthate radical addition-cyclisation sequence
A simple, highly efficient and cheap synthesis of substituted naphthalenes is reported. These aromatic compounds can be easily prepared in acidic or basic conditions from α-tetralones, obtained by a xanthate-mediated addition-cyclisation sequence.
Cordero-Vargas, Alejandro,Perez-Martin, Ines,Quiclet-Sire, Beatrice,Zard, Samir Z.
p. 3018 - 3025
(2007/10/03)
A practical variation on the Paal-Knorr pyrrole synthesis
The radical addition of α-xanthyl ketones to vinyl pivalate gives adducts that are synthetic equivalents of 1,4-ketoaldehydes; treatment with ammonia or primary amines leads to the corresponding pyrroles in high yield.
Quiclet-Sire, Béatrice,Quintero, Leticia,Sanchez-Jimenez, Graciela,Zard, Samir Z.
p. 75 - 78
(2007/10/03)
More Articles about upstream products of 517867-11-7