- Synthesis and spectral studies of macrocyclic Pb(II), Zn(II), Cd(II) and La(III) complexes by template reaction of 1,2-bis(2-formylphenyl)ethane with metal nitrate and various diamine
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Eight new macrocyclic complexes were synthesized by template reaction of 1,4-bis(3-aminopropoxy)butane or (±)-trans-1,2-diaminocyclohexane with metal nitrate and 1,2-bis(2-formylphenyl)ethane and their structures were proposed on the basis of elemental an
- Ilhan, Salih,Temel, Hamdi,Pa?a, Salih,Te?in, Ibrahim
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- Cyclic ligand functionalized mesoporous silica (SBA-15) for selective adsorption of Co2+ion from artificial seawater
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Hard donor atoms (N and O) containing macrocyclic ligand was synthesized and further functionalized with mesoporous SBA-15 materials by chemical modification method. The modification was achieved by the immobilization of 3-chloropropyltriethoxysilane (ClP
- Moorthy, Madhappan Santha,Park, Sung Soo,Selvaraj,Ha, Chang-Sik
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- Through-space electronic communication of zinc phthalocyanine with substituted [60]Fullerene bearing O2Nxaza-crown macrocyclic ligands
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Two new macrocyclic ligands containing 17- and 19-membered O2N3-donor aza-crowns anchored to [60]Fullerene were synthesized and characterized by employing HPLC, electrospray ionization mass (ESI-MS), 1H and 13C NMR, UV–vis, IR spectroscopies, as well as powder X-ray diffraction (PXRD) and thermogravimetric analysis (TGA) in solid state. TGA measurements revealed that upon linking each of these macrocycle rings to [60]Fullerene, the decomposition point measured for [60]Fullerene moiety was increased, indicating on the promoted stability of [60]Fullerene backbone during binding to these macrocyclic ligands. Moreover, the ground state non-covalent interactions of [60]Fullerene derivatives of O2Nx (x?=?2, and 3) aza-crown macrocyclic ligands namely, L1–L4 with zinc phthalocyanine (ZnPc) were also investigated by UV–vis absorption, steady state and time resolved fluorescence spectrophotometry in N-methyl-2-pyrrolidone (NMP). The calculation of Stern-Volmer constants (KSV) indicated on existence of an efficient quenching mechanism comprising of the excited singlet state of ZnPc in the presence of L1–L4. The observation of an appropriate correlation between decrease in fluorescence intensity and lifetime parameters led us to propose the occurrence of a static mechanism for the fluorescence quenching of ZnPc in the presence of L1–L3. The binding constants (KBH) of L1–L4/ZnPc were also determined applying the fluorescence quenching experiments. Meanwhile, the incompatibility of both KSV and KBH values found for L4 was also described in terms of structural features using DFT calculations using the B3LYP functional and 6-31G* basis set.
- Ghanbari, Bahram,Shahhoseini, Leila,Mahlooji, Niloofar,Gholamnezhad, Parisa,Taheri Rizi, Zahra
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- A facile one-pot three-component synthesis of macrocyclic imidazolidines by [3+2] cycloaddition reaction of azomethine ylides
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One-pot three-component synthesis of novel macrocyclic imidazolidines has been accomplished in good yields via a facile [3+2] cycloaddition reaction of azomethine ylide, derived from paraformaldehyde and sarcosine, with various macrocyclic imines as dipol
- Kathiravan, Subban,Raghunathan, Raghavachary
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- Molecular structure, molecular docking, thermal, spectroscopic and biological activity studies of bis-Schiff base ligand and its metal complexes
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Coordination compounds of Fe(III), Zn(II), Ni(II), Co(II), Cu(II), Cd(II) and Mn(II) ions were synthesized from the ligand [4,4′-((((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(methanylylidene))bis(azanylylidene))diphenol]ethane (H2L) derive
- Zayed, Ehab M.,Hindy, Ahmed M.M.,Mohamed, Gehad G.
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- A Bis(Salamo)-Based Fluorogenic Sensor for Highly Selective and Sequential Recognition of Cu2+ and B4O72? Ions in Semi-Aqueous Medium
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A new type of multifunctional bis(salamo)-based fluorogenic sensor H2BS was designed and synthesized. Under the action of VDMF: VH2O = 9: 1, the fluorogenic sensor can identify Cu2+ and B4O7/sub
- Gao, Su-Xia,Xu, Xin,Zhang, Yang,Dong, Wen-Kui
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- Construction and properties of a phototriggered Cd2+ release system
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A phototriggered Cd2+ release complex has been prepared by using benzothiazoline as a ligand. With visible-light (λ ≥ 400 nm) irradiation, bound Cd2+ can be released from the complex, and the ligand is converted into a benzothiazole
- Zhang, Xu,Chen, Yi
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- Synthesis, investigation of the new derivatives of dihydropyrimidines and determination of their biological activity
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We reported of synthesis and investigation of the new biologically active derivatives of dihydropyrimidines 2 and 3. The investigation of structures of compounds by various experiments of NMR spectroscopy revealed the splitting of the signals to doublets
- Maharramov,Ramazanov,Guliyeva,Huseynzada,Hasanova,Shikhaliyev,Eyvazova,Hajiyeva,Mamedov,Aghayev
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- Synthesis and characterization of copper–based anticancer compound; in?vitro interaction studies with DNA/HSA, SOD mimetic, cytotoxic activity and molecular docking investigation
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A new copper(II) complex derived from the ligand ethylene [O,O′–bis{5–{(1E)–(2 hydroxyphenyl)methylene]amino} ? 2–hydroxybenzoic acid] was designed, synthesized and characterized by spectroscopic (IR, UV–Vis, ESI–MS, X–ray diffraction, EPR and elemental a
- Al–Asbahy, Waddhaah M.,Shamsi, Manal
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- A new dinucleating bridging ligand 1,2-bis(2-(1H-imidazo[4,5-f]-[1,10] phenanthrolin-2-yl)phenoxy)ethane and its dinuclear ruthenium(II) complexes: Syntheses, characterization, luminescence, and electrochemical properties
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A new imidazo[4,5-f][1,10]phenanthroline-based dinucleating bridging ligand 1,2-bis(2-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenoxy)ethane (L) and its dinuclear Ru(II) complexes [(bpy)2Ru(L)Ru(bpy)2](ClO 4)4/sub
- Arockia Samy,Alexander
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- Photorelease of La3+ with turn-on fluorescent detection
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Photorelease of La3+ with turn on fluorescent detection is described. Complex (1) is synthesized by treatment 2,2′-(((ethane-1,2- diylbis(oxy)bis(2,1-phenylene))bis(methanylylidene)) bis(azanylylidene))diphenol with LaCl3·7H2/s
- Hao, Yongchao,Zhang, Xu,Chen, Yi
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- Fluorescent chemical sensor based on double N2O2 cavities for continuous recognition of Cu2+ and Al3+
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A fluorescent chemical sensor based on a bis(salamo)-like tetraoxime H2LS was designed and synthesized. The chemical sensor uses double N2O2 cavities as sensing elements, which can be combined with specific meta
- Bian, Ruo-Nan,Dong, Wen-Kui,Li, Ya-Juan,Wang, Ji-Fa,Zhang, Yang
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- Synthesis, physico-chemical, structure and supramolecular properties of pinacolophanes: Versatile synthetic precursors to stilbenophanes
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Novel pinacolophanes tethered by methyl and ethyl chains were synthesised and characterised. The stereochemistry of these small-sized cyclophanes was determined by NMR spectral data as well as by single-crystal X-ray analysis. Intramolecular hydrogen bond
- Darabi, Hossein Reza,Karouei, Mohammad Hashemi,Tehrani, Mohammad Jafar,Aghapoor, Kiomars,Ghasemzadeh, Mitra,Neumueller, Bernhard
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- Highly sensitive sensing of Fe(III) harnessing Schiff based ionophore: An electrochemical approach supported with spectroscopic and DFT studies
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The vital role of iron in biological systems and health implications posed to humans due to associated toxicity by the consumption of iron contaminated food or drinking water and exposure to other environmental sectors demand sensitive methods for its det
- Kaur, Sarbjeet,Shiekh, Bilal Ahmad,Kaur, Damanjit,Kaur, Inderpreet
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- Efficient synthesis of novel benzylidene barbituric and thiobarbituric acid derivatives containing ethyleneglycol spacers
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Knoevenagel condensation reaction of ethylene glycol-based aromatic aldehyde with barbituric acid derivatives in ethanol produced novel benzylidene barbituric and thiobarbituric acid derivatives which contain good yields of ethylene glycol spacers. Structures of the products were deduced from their IR, 1H-NMR, and 13C-NMR spectroscopy and mass spectra.
- Faryabi, Malihe,Sheikhhosseini, Enayatollah
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- Synthesis and crystal structure of 2,2'-(1,2-Ethylenedioxy)bisbenzaldehyde O,O'-diethyldioxime
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The compound, 2,2'-(1,2-ethylenedioxy)-bis-benzaldehyde O,O'-diethyldioxime, has been synthesized by 2,2'-(1,2-ethylenedioxy)- bisbenzaldehyde O,O'-diethyldioxime and ethoxyamine hydrochloride in ethanolic solution and characterized structurally by X-ray
- Zhao, Li,Zhang, Yu-Jie,Zhang, Shou-Ting,Guo, Hong-Xia,Cheng, Qian
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- Dinuclear platinum(II) complexes of imidazophenanthroline-based bridging ligands as potential anticancer agents: synthesis, characterization, and in vitro cytotoxicity studies
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Abstract: The synthesis and characterization of the dinucleating ligands 1,2-bis(2-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenoxy)ethane (L1) and 1,2-bis(2-(1H-imidazo[4,5-f][1, 10]phenanthrolin-2-yl)phenoxy)hexane (L2) and their dinuclear complexes [
- Alexander, Carlson,Prajith,Priyanka,Nithyakumar,Arockia Samy
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- A novel fluorescent chemosensor for Cu2+ ion based on a new hexadentate ligand receptor: X-ray single crystal of the perchlorate salt of the ligand, ion selectivity assays and TD-DFT study
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New hexadentate chelates, H2L1 and L1, were synthesized. The Schiff base imine ligand, L1, was prepared by reaction of 2,2′-[ethane-1,2-diylbis(oxy)]dibenzaldehyde and propanolamine, and characterized by infrare
- Bahrampour, Marzyeh,Fausto, Rui,Golbedaghi, Reza,Justino, Licínia L. G.
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- A comparative molecular structure – NLO activity study of ortho-bridged dibenzaldehydes: Synthesis, crystal structure, SHG, and DFT studies
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Structural and second order nonlinear optical characteristics of four ortho-bridged dibenzaldehydes with alkyloxy- and xylenyloxy linkers are compared from the XRD, UV-Vis-NIR spectroscopic, SHG, and DFT studies. Interruption of electron polarization by π
- Jothi, A. Irudaya,Paul, M. Wilson Bosco,Alexander
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- Green synthesis of novel bis(hexahydro-1H-xanthene-1,8(2H)-diones) employing p-toluenesulfonic acid (p-TSA) as a solid acid catalyst
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Green synthesis of novel bis(hexahydro-1H-xanthene-1,8(2H)-diones) which are linked to aliphatic or aromatic spacers via ether or ester linkages were performed in good to excellent yields by the reaction of 5,5-dimethyl-1,3-cyclohexanedione with the appropriate bis-aldehydes using p-TSA as an organic acid solid catalyst. The reaction of the bis-aldehydes with barbituric acid or 1,3-dimethylbarbituric acid instead of 5,5-dimethyl-1,3-cyclohexanedione afforded the corresponding Knoevenagel condensation adducts in good yield.
- Darweesh, Ahmed F.,Salama, Soad K.,Abdelhamid, Ismail A.,Elwahy, Ahmed H. M.
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p. 471 - 484
(2020/10/30)
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- Co(II) Schiff base Complexes Encapsulated in the Nanopores of Zeolite Y as Heterogeneous Catalysts for Selective Epoxidation of Alkenes with Molecular Oxygen
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Abstract: Co(II) macrocyclic Schiff base complex nanoparticles have been encapsulated in the nanopores of zeolite Y. The new Schiff base complexes entrapped in the nanoreactor of zeolite Y were characterized by several techniques: chemical analysis and spectroscopic methods (FT-IR, XRD, and DRS). These complexes (neat and encapsulated) were used for epoxidation of alkenes with O2 as oxidant in different solvents. The catalyst demonstrated excellent activity for a variety of alkenes in a mild, inexpensive and efficient protocol. Reaction parameters including temperature, catalyst amount and solvent were screened by reaction time. The recycling experiment results indicated that the catalysts were highly stable and maintained activity and selectivity even after being used for five cycles.
- Banaei, A. R.,Pourali, A. R.,Rezazadeh, B.,Tabari, S.
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p. 424 - 437
(2021/07/16)
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- Synthesis, antitumor activity, enzyme assay, DNA binding and molecular docking of Bis-Schiff bases of pyrazoles
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A novel series of Bis-Schiff bases of pyrazoles 9–24 were synthesized by the direct condensation of 5-aminopyrazoles 4a–d with dialdehydes 8a–d in ethanol. The newly synthesized Bis-Schiff bases of pyrazoles 9–24 were characterized and confirmed by analyt
- Morsy, Nesrin M.,Hassan, Ashraf S.,Hafez, Taghrid S.,Mahran, Mohamed R. H.,Sadawe, Inass A.,Gbaj, Abdul M.
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- Novel 2-cyanoacrylamido-4,5,6,7-tetrahydrobenzo[b]thiophene derivatives as potent anticancer agents
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Ethyl 2-acrylamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate as well as its corresponding bis-derivatives, 5–10, with aliphatic linkers were synthesized, fully characterized, and tested as novel anticancer agents. The targeted compounds, 5–10, wer
- Sroor, Farid M.,Aboelenin, Mohamad M.,Mahrous, Karima F.,Mahmoud, Khaled,Elwahy, Ahmed H. M.,Abdelhamid, Ismail A.
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- DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA
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Provided herein are compounds and methods for modulating abnormal repeat expansions of gene sequences. More particularly, provided are dimeric inhibitors of RNA and the uses of such inhibitors in regulating nucleotide repeat expansions, e.g., to treat Myotonic Dystrophy Type 1 (DM1), Myotonic Dystrophy Type 2 (DM2), Fuchs dystrophy, Huntington Disease, Amyotrophic Lateral Sclerosis, or Frontotemporal Dementia.
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Paragraph 0226; 0227; 0228
(2020/07/16)
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- Preparation method and application of 2-(2-salicylic aldehyde)ethyoxyl-phenyl fulleropyrrolidine
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The invention belongs to the technical field of organic synthesis, particularly relates to a preparation method of N-methyl-2-{[2-(2-salicylic aldehyde)ethyoxyl]-phenyl}-3,4-fulleropyrrolidine, and relates to application of fulleropyrrolidine as a catalys
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Paragraph 0078; 0081; 0082
(2019/05/04)
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- Schiff base complexes of Mo(VI) immobilized on functionalized graphene oxide nano-sheets for the catalytic epoxidation of alkenes
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Mo(VI) tetradentate Schiff base complexes were covalently immobilized onto chemically functionalized graphene oxide (GO) using 3-(tri-methoxysilyl) propylamine as a coupler. The resulting heterogeneous catalysts have been characterized by FTIR, DRS, XRD, SEM, TGA, and atomic absorption spectroscopy (AAS). These catalysts were applied in epoxidation of cyclooctene and other olefins. The catalytic procedures with all catalysts were optimized for different parameters such as oxidant, solvent and temperature. Recycling results indicated that the catalysts were highly stable and maintained activity and selectivity even after being used for five cycles.
- Rezazadeh, Behnam,Pourali, Ali Reza,Banaei, Alireza,Behniafar, Hossein
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p. 3401 - 3416
(2019/11/21)
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- Synthesis, X-ray crystallography, thermogravimetric analysis and spectroscopic characterization of isostructural one-dimensional coordination polymers as sorbents for some anions
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A new diaza-macrocyclic ligand bearing two pyridine side arms (L2) was synthesized and characterized by single-crystal X-ray diffraction (SCXRD), elemental analysis, FT-IR, and 1H and 13C NMR methods. The macrocyclic ligand showed a great tendency to act as an appropriate tecton in the formation of coordination polymers in the presence of Cu, Ni, Mn, Pb, and Cd chlorides. Five new isostructural one dimensional metal-organic coordination polymers [{M(Cl)2}(L)4] (M = Cu, Ni, Mn, Pb, Cd) were prepared in DMSO or DMF and characterized by elemental analysis, IR spectroscopy, TGA-DTG, powder X-ray diffraction (PXRD) and single-crystal X-ray diffraction. All of the polymers were employed as solid sorbents for Cr(vi) anions in aqueous solution. Within the series, the Pb(ii) coordination polymer demonstrated notable absorption behavior for sorption of Cr(vi) and some oxo-anions such as MoO42-, WO42-, and MnO4- (environmental concern anions), together with HPO42-. The anion adsorption properties were attributed to the presence of surface positive charge on the coordination polymer.
- Ghanbari, Bahram,Shahhoseini, Leila,Owczarzak, Agata,Kubicki, Maciej,Kia, Reza,Raithby, Paul R.
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p. 1783 - 1796
(2018/04/03)
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- Pinacolophanes as versatile precursor for the practical synthesis of tolanophanes
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Abstract: A new strategy for the synthesis of tolanophanes was investigated. The coupling of bridged dialdehydes gave selectively the corresponding monomer of pinacolophanes in quantitative yields under a simple and clean reaction condition. Without any f
- Darabi, Hossein Reza,Rastgar, Saeed,Aghapoor, Kioumars,Mohsenzadeh, Farshid
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p. 1121 - 1124
(2017/12/26)
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- Exploitation of Intramolecular Glaser-Eglinton-Hay Macrocyclization for the Synthesis of New Classes of Optically Active Aza-Oxo-Thia Polyether Macrocycles from Amino Alcohol Building Blocks
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We report an intramolecular Glaser-Eglinton-Hay coupling as an unprecedented route for assembling optically active aza-oxo polyether macrocycles containing a 1,3-diyne unit from enantiopure amino alcohol building blocks and suitable linkers. Furthermore, the conversion of the 1,3-diyne unit of the aza-oxo polyether macrocycles into a thiophene ring led to the assembly of new classes of optically active aza-oxa-thia (heterotopic) polyether macrocycle analogues of classical 18-C-6 and 18-C-5 systems.
- Babu, Srinivasarao Arulananda
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supporting information
p. 253 - 259
(2017/01/25)
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- Spacer length dependent architectural diversity in bis-dipyrrin copper(II) complexes
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A series of copper(ii) complexes (1-9 and 3′) derived from bis-dipyrrin ligands (L1-L9 and L3′) with diverse spacer lengths [-(CH2)n-] have been described. Structural diversities in these complexes have been explicitly established by spectral and structural studies on these and a closely related nickel(ii) complex (3′′). All the ligands and complexes have been thoroughly characterized by spectroscopic studies (ESI-MS, IR, 1H, 13C NMR, UV/vis) and structures of 2, 3′, 3′′, 6, 8 and 9 were determined by X-ray single crystal analyses. It has been unambiguously established that ligands with n ≤ 6 gave heteroleptic binuclear (1-5), while those with n ≥ 7 yielded homoleptic mononuclear (6-9) bis-dipyrrinato complexes. Spectral and structural studies revealed distorted square planar (1-5) and distorted tetrahedral geometries (6-9) about the copper(ii) centre in these complexes which has further been evidenced by EPR and electrochemical studies. Structural differences based on the odd and even number of methylene spacers in these complexes have been supported by DFT studies. A line between the syn- and anti-conformations of the complexes has been drawn on the basis of a limiting spacer length.
- Paitandi, Rajendra Prasad,Singh, Roop Shikha,Mukhopadhyay, Sujay,Kumar, Ashish,Pandey, Daya Shankar
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p. 5420 - 5430
(2017/04/28)
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- An entry into new classes of optically active aza-oxo polyether macrocycles via the ring closing metathesis-based macrocyclization
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We report the application of ring closing metathesis-based macrocyclization route for synthesizing 22–36 membered optically active aza-oxo crowns/polyether macrocycles. While the RCM-based synthesis of polyether macrocycles was well explored in the literature, the synthesis of optically active polyether macrocycles was not explored via the RCM reaction. Accordingly, the present method reveals an efficient assembling of a library of new classes of optically active aza-oxo polyether macrocycles from optically active RCM precursors, which were assembled from easily available linkers, chiral α-methylbenzylamine and amino alcohol building blocks under simple reaction conditions.
- Naveen,Babu, Srinivasarao Arulananda
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supporting information
p. 5690 - 5694
(2016/11/28)
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- Ring-closing metathesis reaction-based synthesis of new classes of polyether macrocyclic systems
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Ring closing metathesis (RCM) reactions of suitable substrates having terminal olefins, which are assembled from various linkers and hydroxy benzaldehydes and syntheses of a wide range of 16-30 membered, new crown ether-type polyether, aza-polyether, bis aza-polyether macrocycles and dilactone moiety embedded polyether macrocycles (macrolides) are reported. After the ring-closure reaction, installation of different functional groups and functional group modification on the periphery of the synthesized polyether/crown ether macrocycles obtained in the RCM reactions are accomplished using the epoxidation, oxidation and catalytic hydrogenation-based synthetic transformations. Along this line, the syntheses of a variety of polyether macrocycles possessing epoxide or α-hydroxy ketone or 1,2-diol functionalities at the periphery have been shown. Furthermore, the synthesized α-hydroxy ketone functionality installed polyether macrocycles were subjected to the allylation and Reformatsky type reactions to obtain homoallyl alcohol moiety-based and lactone ring-appended polyether macrocycles.
- Naveen,Babu, Srinivasarao Arulananda
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supporting information
p. 7758 - 7781
(2015/09/08)
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- Structures of NHC Hg(II) and Ag(I) complexes and selective recognition of nitrate anion
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A series of bis-benzimidazolium (or bis-imidazolium) salts, and their eight N-heterocyclic carbene mercury(II) and silver(I) complexes (1-8) have been synthesized and characterized. Complexes 1-4 and 6 contain similar macrometallocycles formed via one bid
- Liu, Qing-Xiang,Zhao, Zhi-Xiang,Zhao, Xiao-Jun,Wei, Qing,Chen, Ai-Hui,Li, Hui-Long,Wang, Xiu-Guang
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p. 1358 - 1373
(2015/02/19)
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- One-pot synthesis of bis(4,5-diphenylimidazol-2-yl-phenyl)glycols and evaluation of their antimicrobial activity
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Abstract A new series of bis(4,5-diphenylimidazol-2-yl-phenyl)glycols were synthesized by reaction of bis(formylphenyl)glycols with benzil/benzoin and ammonium acetate in presence of iodine/acetic acid in ethanol. All newly synthesized compounds were char
- Linga Goud,Ramesh,Ashok,Prabhakar Reddy
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p. 673 - 678
(2015/05/05)
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- Synthesis and antimicrobial evaluation of novel bis-β-lactam grafted macrocycles
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A series of macrocyclic bis-β-lactams has been synthesized in three good yielding steps using a Staudinger [2+2] cycloaddition reaction of ketene derived from phenoxyacetyl chloride as the key step. The reaction provided a diastereomeric mixture of cis-an
- Arumugam, Natarajan,Almansour, Abdulrahman I.,Kumar, Raju Suresh,Rajesh, Raju,Periyasami, Govindasami,Raghunathan, Raghavachary
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p. 730 - 737
(2015/04/14)
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- Synthesis and structural characterization of four novel bisoxime-type compounds based on 2,2'-(Ethylenedioxy)bisbenzaldehyde
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A series of bisoxime compound have been synthesized by the reaction of 2,2'-(ethyylenedioxy) bisbenzaldehyede with hydroxylamine hydrochloride methoxyamine hydrochloride ethyoxylamine hydrochloride or 3-aminoacetophenone oxime in hot ethanol medium, respe
- Wang, Li,Gao, Su-Xia,Zhang, Yang,Li, Gang,Zhang, Yu-Jie
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p. 6272 - 6274
(2015/02/19)
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- Benzohydroxamic acids as potent and selective anti-HCV agents
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A diverse collection of 40 derivatives of benzohydroxamic acid (BHAs) of various structural groups were synthesized and tested against hepatitis C virus (HCV) in full-genome replicon assay. Some of these compounds demonstrated an exceptional activity, suppressing viral replication at sub-micromolar concentrations. The compounds were inactive against key viral enzymes NS3, and NS5B in vitro assays, suggesting host cell inhibition target(s). The testing results were consistent with metal coordination by the BHAs hydroxamic group in complex with a target(s). Remarkably, this class of compounds did not suppress poliomyelitis virus (PV) propagation in RD cells indicating a specific antiviral activity of BHAs against HCV.
- Kozlov, Maxim V.,Kleymenova, Alla A.,Romanova, Lyudmila I.,Konduktorov, Konstantin A.,Smirnova, Olga A.,Prasolov, Vladimir S.,Kochetkov, Sergey N.
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supporting information
p. 5936 - 5940
(2013/10/22)
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- N-Heterocyclic carbene silver(I), palladium(II) and mercury(II) complexes: Synthesis, structural studies and catalytic activity
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The bis-benzimidazolium salts, 1,2-bis[2-(N-R-benzimidazolemethyl)phenoxy] ethane chloride (L1H2: R = Et, L2H2: R = nBu), 1,3-bis[2-(N-R-benzimidazolemethyl)phenoxy]propane chloride (L3H2: R = nPr, L4H 2: R = nBu) and bis[N-R-benzimidazolemethyl]mesitylene 2X (L5H2: R = nBu, X = I; L6H 2: R = PyCH2, X = Br and L7H2: R = PhCH2, X = Br), as well as their eight NHC silver(i), palladium(ii) and mercury(ii) complexes, [(L1Ag)2Ag2Cl 4] (1), [L1(PdCl2CH3CN)2] (2), [(L2Ag)2AgCl2][AgCl2] (3), [(L3Ag2Cl2)n] (4), [(L 4Ag2Cl2)n] (5), [L 5HgI][HgI4]0.5 (6), [L6Hg][HgBr 4] (7) and [L7Ag][(NO3)0.76Br 0.24] (8) have been prepared and characterized. The complexes 1-8 adopt four different structures: (1) with bis-macrometallocycles connected via a Ag2Cl4 unit for 1 and via a AgCl2 unit for 3, (2) an open structure formed via one ligand and two metal atoms for 2, (3) 1D polymeric chains formed by the monomers of a cage-like cavity via weak Ag...Cl bonds (monomer: L3Ag2Cl2 for 4 and L4Ag2Cl2 for 5) and (4) a macrocyclic structure formed by one ligand and one metal for 6-8. In the crystal packing of these complexes, 1D supramolecular chains, 2D supramolecular layers and 3D supramolecular architectures are formed via intermolecular weak interactions, including π-π interactions, hydrogen bonds, C-H...π contacts and weak Hg...Br bonds. Particularly, the catalytic activity of the NHC palladium(ii) complex 2 in Suzuki-Miyaura cross-coupling reactions was studied.
- Liu, Qing-Xiang,Wang, Hong,Zhao, Xiao-Jun,Yao, Zhao-Quan,Wang, Zhi-Qiang,Chen, Ai-Hui,Wang, Xiu-Guang
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experimental part
p. 5330 - 5348
(2012/09/08)
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- Design and synthesis of rhodamine based chemosensors for the detection of Fe3+ ions
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The number and nature of coordinating entities as well as the size of chelating cavity in rhodamine based chemosensors were tuned to enhance the selectivity and sensitivity for Fe3+ ions. An intense pink color development and enhancement in flu
- Chereddy, Narendra Reddy,Suman, Koorathota,Thennarasu, Sathiah,Korrapati, Purna Sai,Mandal, Asit Baran
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p. 606 - 613,8
(2020/07/30)
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- Rhodium(II)-catalyzed cyclization of bis(N-tosylhydrazone)s: An efficient approach towards polycyclic aromatic compounds
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Ahead of the PAC: Polycyclic aromatic compounds (PACs) can be easily accessed by the combination of Suzuki-Miyaura cross-coupling and a [Rh 2(OAc)4]-catalyzed carbene reaction using easily available bis(N-tosylhydrazone)s as intermediates (see scheme; Ts=4-toluenesulfonyl). Copyright
- Xia, Ying,Liu, Zhenxing,Xiao, Qing,Qu, Peiyuan,Ge, Rui,Zhang, Yan,Wang, Jianbo
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supporting information; experimental part
p. 5714 - 5717
(2012/07/28)
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- Simple synthesis of a new family of 22- to 28-membered macrocycles containing two chalcone moieties
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A new family of 22- to 28-membered tetrabenzo-macrocycles containing two chalcone moieties has been synthesized from 2-hydroxybenzaldehyde and 2'-hydroxyacetophenone through phenol alkylation with α,ω- dibromoalkanes followed by Claisen-Schmidt reaction u
- Mondal, Rina,Mandal, Tapas K.,Mallik, Asok K.
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p. 95 - 110,16
(2020/09/02)
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- A triple-probe channel NO2S2-macrocycle: Synthesis, sensing characteristics and crystal structure of mercury(II) nitrate complex
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A triple-probe channel type chemosensor based on an NO2S 2-macrocycle functionalized with phenyltricyanovinyl group was synthesized and its sensing characteristics were examined. The pink-red solution of L changed selectively to pale
- Lee, Ji-Eun,Choi, Kyu Seong,Seo, Moo Lyong,Lee, Shim Sung
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scheme or table
p. 2031 - 2035
(2010/11/18)
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- Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity
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Versatile simple efficient routes with good to excellent yields towards different functionalized 1,ω-bis(1,2,4-triazoles), 21-28 membered 1,2,4-triazole fused macrocyclic and/or lariat macrocyclic oxaazathia crown Schiff bases and/or amines have been investigated. Antimicrobial screening of some selected compounds revealed different inhibitory effects against Aspergillus fumigatus RCMB 002008 (1), Penicillium italicum RCMB 001018 (1), Syncephalastrum racemosum RCMB 016001 Candida albicans RCMB 005003, Staphylococcus aureus RCMB 106-001 (1), Pseudomonas aeruginosa RCMB 102-002, Bacillus subtilis RCMB 101-001 and Escherichia coli RCMB 103-001.
- Khalil, Nasser S.A.M.
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experimental part
p. 5265 - 5277
(2011/01/04)
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- Stereoselective synthesis of oxazolidine, hexahydropyrrolo [2,1-b] oxazole, and tetrahydro-2H-oxazolo [3,2-c] thiazole grafted macrocycles through intramolecular 1,3-dipolar cycloaddition reaction
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A facile one-pot synthesis of oxazolidine, hexahydropyrrolooxazole and tetrahydro-2H-oxazolothiazole grafted macrocycles through intramolecular 1,3-dipolar cycloaddition reaction (1,3-DC reaction) is reported. X-ray diffraction studies and 2D NOESY experi
- Purushothaman,Raghunathan
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scheme or table
p. 6848 - 6850
(2010/04/29)
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- Rationally-designed S-chiral bissulfinamides as highly enantioselective organocatalysts for reduction of ketimines
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We recently reported the first example of S-chiral organocatalysts, that are highly efficient and enantioselective in substoichometric amounts, and which use a chiral monosulfinamide group as Lewis base to activate trichlorosilane (HSiCl3) to reduce N-arylketimines. Aplausible mechanism involving two molecules of the monosulfinamde catalyst for the activation of HSiCl 3 prompted us to design S-chiral bissulfinamides as new catalysts. We herein describe our findings that an easily prepared S-chiral bissulfinamide bearing a five-methylene linkage not only inherited the excellent substrate generality from the monosulfinamide catalysts, but also exhibited further improved enantioselectivity.
- Pei, Dong,Zhang, Yu,Wei, Siyu,Wang, Meng,Sun, Jian
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supporting information; experimental part
p. 619 - 623
(2009/04/21)
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- Synthesis and spectral studies of macrocyclic Cu(II), Ni(II) and Co(II) complexes by template reaction of 1,4-bis(3-aminopropoxy)butane with metal(II) nitrate and salicylaldehyde derivatives
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Six new macrocyclic complexes were synthesized by template reaction of salicylaldehyde derivatives with 1,4-bis(3-aminopropoxy)butane and metal(II) nitrate. The metal to ligand ratio of the complexes was found to be 1:1. The Cu(II) complexes are proposed
- Ilhan, Salih,Temel, Hamdi
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experimental part
p. 157 - 166
(2009/04/13)
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- Silver(I) and copper(I) coordination polymers based on thiaoxa-macrocycles
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Two S2O2-macrocycles with different ring size (L 1: 17- and L2: 18-membered) were synthesised and structurally characterised by X-ray analysis. Reactions of L1 and L2 with silver(I) salts (
- Hyun, Jee Kim,Mi, Ryoung Song,So, Young Lee,Jai, Young Lee,Shim, Sung Lee
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scheme or table
p. 3532 - 3539
(2009/02/07)
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- Temperature-dependent synthesis of metal-organic frameworks based on a flexible tetradentate ligand with bidirectional coordination donors
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Using a temperature-dependent synthetic approach, four distinct new silver(I) coordination polymers resulting from the different conformations adopted by the flexible ligand at different temperatures were obtained. Copyright
- Dong, Yu-Bin,Jiang, You-Yun,Li, Jie,Ma, Jian-Ping,Liu, Feng-Ling,Tang, Bo,Huang, Ru-Qi,Batten, Stuart R.
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p. 4520 - 4521
(2007/10/03)
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