A STEREOSELECTIVE SYNTHESIS OF β,γ-DISUBSTITUTED ALLYLIC ALCOHOLS OF Z-CONFIGURATION
Reaction of alkyllithiums 1 with isoprene epoxide 2 gives β,γ-disubstituted allylic alcohols 3 of Z-configuration.The reaction of ?-lithiotricyclene as alkyllithium gives α-santalol 5, which is one of the main constituents in East Indian sandalwood oil.