- Synthesis method and application of amide crystal compound
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A synthesis method of an amide crystal compound (I) with the following structural formula and unit cell parameters comprises the following steps: under water-free and oxygen-free conditions, weighing2.0968g of benzophenone hydrazone and 1.9990g of copper acetate monohydrate, putting the raw materials into a 250mL two-neck flask, adding 100mL of chlorobenzene as a solvent, carrying out reflux reaction for 48 hours, carrying out column chromatography separation, carrying out eluting with petroleum ether/dichloromethane (3/7), and naturally volatilizing a collected first component point to obtain single crystal N-acetylamino benzophenone hydrazone. According to the application of the amide crystal compound (I), a certain catalytic effect is shown in the self-condensation reaction of benzophenone imine as a catalyst, and the conversion rate of benzophenone imine reaches 53%.
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Paragraph 0012; 0018-0019
(2020/05/14)
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- Synthesis of Isoquinoline Derivatives via Palladium-Catalyzed C?H/C?N Bond Activation of N-Acyl Hydrazones with α-Substituted Vinyl Azides
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A palladium-catalyzed cyclization of N-acetyl hydrazones with vinyl azides has been developed. Various substituted isoquinolines, including diverse fused isoquinolines can be prepared via this protocol in moderate to good yields. Mechanistic studies suggest that α-substituted vinyl azide serves as an internal nitrogen source. Also, C?H bond activation and C?N bond cleavage have been realized using hydrazone as directing group. (Figure presented.).
- Jiang, Huanfeng,Nie, Biao,Ren, Qingyun,Wu, Wanqing,Zeng, Wei,Zhang, Ji,Zhang, Yingjun
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supporting information
(2020/02/25)
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- Microwave assisted solvent-free C-H amination by silica-supported manganese dioxide
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An effective and convenient method has been developed for the preparation of 1-unsubstituted 1H-indazoles via C-H amination of N-acetylhydrazones in the presence of a catalytic amount of manganese dioxide under microwave irradiation. This new method featured easy operation and relatively short reaction-time.
- Cao, Sufen,Duan, Wenhu
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p. 2390 - 2394
(2016/05/19)
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- PESTICIDAL METHODS USING HETEROCYCLIC COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS
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The present invention relates to pesticidal methods for the use and application of substituted heterocyclic compounds of formula (I) and the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising the same. The invention also r
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Page/Page column 52
(2013/10/21)
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- NOTES ON THE REACTIONS OF KETONE ACYLHYDRAZONES UNDER ACYLATION CONDITIONS
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The reactions of the acetophenone and fluorenone acylhydrazones under acylation conditions were investigated.The structures of the diacylhydrazones and 1,3,4-oxadiazolines formed were proved by UV, IR, (1)H- and (13)C-NMR spectroscopical as well as by MS
- Somogyi, L
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p. 5187 - 5190
(2007/10/02)
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- Monochromatic Light-induced Reactions of Benzophenone Hudrazones and the N-Acetyl Derivatives in Carbon Tetrachloride in the Presence of Oxygen
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Irradiation of hydrazones of benzophenone, 4-methylbenzophenone and 4-methoxybenzophenone in carbon tetrachloride with monochromatic light in the presence of oxygen afforded the corresponding azine, resulting from N-N bond cleavage, as the major product together with the hydrazone hydrochloride.In contrast to the hydrazones, benzophenone acetylhydrazone in carbon tetrachloride in the presence of oxygen afforded an unstalbe hydroperoxide as the only product, on photolysis with monochromatic light (288 +/- 8 nm); this product was transformed spontaneously into benzophenone on evaporation of the solvent at room temperature. 4-Methylbenzophenone acetylhydrazone and 4-methoxybenzophenone acetylhydrazone reacted in a manner similar to benzophenone acetylhydrazone.Irradiation of benzophenone diacetylhydrazone with 266 +/- 8 nm light under conditions analogous to the photo-reactions of hydrazones and acetylhydrazones resulted in loss of an acetyl group, resulting in N-CO bond cleavage to afford acetylhydrazone.The mechanism of the photooxygenation of benzophenone acetylhydrazones is interpreted in terms of chlorine radical-induced autoxidation.
- Suginome, Hiroshi,Uchida, Tsutomu
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p. 3225 - 3231
(2007/10/02)
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