Development of AC265347-Inspired Calcium-Sensing Receptor Ago-Positive Allosteric Modulators
The calcium-sensing receptor (CaSR) is a clinical target in the treatment of hyperparathyroidism and related diseases. However, clinical use of approved CaSR-targeting drugs such as cinacalcet is limited due to adverse side effects including hypocalcaemia
Dinh, Le Vi,DeBono, Aaron,Keller, Andrew N.,Josephs, Tracy M.,Gregory, Karen J.,Leach, Katie,Capuano, Ben
p. 3451 - 3462
(2021/08/03)
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