- Research on controllable degradation of sulfonylurea herbicides
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In order to seek ecologically safer and environmentally benign sulfonylurea herbicides (SU), insight into the structure/bioassay/soil degradation tri-factor relationship was first established. With the introduction of various groups (alkyl, nitro, halogen, cyano etc.) at the 5th position of its benzene ring, structural derivatives of chlorsulfuron were designed, synthesized, and evaluated for their herbicidal activity. The structures of the title compounds were confirmed by infrared spectroscopy, ultraviolet spectroscopy, 1H and 13C NMR, mass spectrometry, elemental analysis and X-ray diffraction. Bioassay results confirmed that most derivatives retained their superior herbicidal activities in comparison with chlorsulfuron. After investigating the soil degradation behavior of each molecule under set conditions, it was found that structures with electron-withdrawing substituents at the 5th position of the benzene ring retained their long degradation half-lives, yet the introduction of electron-donating substituents accelerated the degradation rate. These results will provide a valuable clue to further explore the potential controllable degradation of SU and other herbicides, and to discover novel herbicides that are favorable for environmentally and ecologically sustainable development.
- Hua, Xue-Wen,Chen, Ming-Gui,Zhou, Shaa,Zhang, Dong-Kai,Liu, Ming,Zhou, Sha,Liu, Jing-Bo,Lei, Kang,Song, Hai-Bin,Li, Yong-Hong,Gu, Yu-Cheng,Li, Zheng-Ming
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p. 23038 - 23047
(2016/03/12)
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- Enhanced chemoselective hydrogenation through tuning the interaction between pt nanoparticles and carbon supports: Insights from identical location transmission electron microscopy and x?ray photoelectron spectroscopy
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Ultrasmall-sized platinum nanoparticles (Pt NPs) (~1 nm) supported on carbon nanotubes (CNTs) with nitrogen doping and oxygen functional groups were synthesized and applied in the catalytic hydrogenation of nitroarenes. The advanced identical location transmission electron microscopy (IL-TEM) method was applied to probe the structure evolution of the Pt/CNT catalysts in the reaction. The results indicate that Pt NPs supported on CNTs with a high amount of nitrogen doping (Pt/H-NCNTs) afford 2-fold activity to that of Pt NPs supported on CNTs with oxygen functional groups (Pt/oCNTs) and 4-fold to that of the commercial Pt NPs supported on active carbon (Pt/C) catalyst toward nitrobenzene. The catalytic performance of Pt/H-NCNTs remained constant during four cycles, whereas the activity of the Pt/oCNTs was halved at the second cycle. Compared with Pt/oCNTs, Pt/H-NCNTs exhibited a higher selectivity (>99%) in chemoselective hydrogenation of halonitrobenzenes to haloanilines due to the electron-rich chemical state of Pt NPs. The strong metal?support interaction along with the electron-donor capacity of nitrogen sites on H-NCNTs are capable of stabilizing the Pt NPs and achieving related catalytic recyclability as well as approximately 100% selectivity. The catalyst also delivers exclusively selective hydrogenation toward nitro groups for a wide scope of substituent nitroarenes into their corresponding anilines.
- Shi, Wen,Zhang, Bingsen,Lin, Yangming,Wang, Qi,Zhang, Qiang,Su, Dang Sheng
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p. 7844 - 7854
(2018/05/23)
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- In situ production of silver nanoparticles on an aldehyde-equipped conjugated porous polymer and subsequent heterogeneous reduction of aromatic nitro groups at room temperature
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In a metal-free procedure, chelating thiol groups and an electrophile react to assemble a robust, conjugated porous polymer with pendant aldehyde functionalities. These groups are able to reduce Ag(I) ions to generate, in situ, Ag(0) nanoparticles evenly dispersed in the polymer matrix. The Ag(0)-polymer composite enables selective reduction of aromatic nitro compounds as a heterogeneous catalyst, and can be conveniently recycled multiple times.
- Liu, Jie,Cui, Jieshun,Vilela, Filipe,He, Jun,Zeller, Matthias,Hunter, Allen D.,Xu, Zhengtao
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supporting information
p. 12197 - 12200
(2015/07/27)
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- Efficient and highly selective boron-doped carbon materials-catalyzed reduction of nitroarenes
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Exploring the potential catalytic applications of boron-doped carbon materials is a fascinating challenge. Here we describe that boron-doped onion-like carbon and carbon nanotubes as metal-free catalysts exhibit excellent catalytic activity and stability in nitroarene reduction under a stoichiometric amount of reductant.
- Lin, Yangming,Wu, Shuchang,Shi, Wen,Zhang, Bingsen,Wang, Jia,Kim, Yoong Ahm,Endo, Morinobu,Su, Dang Sheng
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p. 13086 - 13089
(2015/08/18)
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- THERAPEUTIC AGENT FOR CEREBRAL INFARCTION
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The invention provides a therapeutic drug for ischemic stroke. The therapeutic drug has the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof, as an active ingredient.
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- ARYLSULFONAMIDE CCR3 ANTAGONISTS
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Provided herein are arylsulfonamides that are useful for modulating CCR3 activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a CCR3-mediated disorder, disease, or condition.
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Page/Page column 35
(2011/10/10)
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- An efficient method for aryl nitro reduction and cleavage of azo compounds using iron powder/calcium chloride
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A novel, efficient Fe/CaCl2 system is revealed for the reduction of nitroarenes and reductive cleavage of azo compounds by catalytic transfer hydrogenation (CTH). The selective reduction of nitro compounds in the presence of sensitive functional groups including halides, carbonyl, hydroxyl, aldehyde, methyl, methoxy, acetyl, nitrile, and ester substituents with an excellent yields is reported. The simple experimental procedure and easy purification make the protocol advantageous
- Chandrappa,Vinaya,Ramakrishnappa,Rangappa
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experimental part
p. 3019 - 3022
(2011/03/17)
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- Therapeutic modulation of PPARgamma activity
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Modulators of PPARγ activity are used in methods of treating and/or preventing conditions such as osteoporosis, Alzheimer's disease, psoriasis and acne, and cancer.
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Page/Page column 70
(2010/02/14)
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- Compounds for the modulation of PPARgamma activity
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Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.
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- Process for preparing aromatic amines
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The present invention relates to a process for preparing aromatic amines by reacting an aromatic nitro compound with carbon monoxide in a solvent mixture comprising water and a water-insoluble organic solvent by means of a catalyst comprising palladium and a water-soluble phosphine under a pressure of from 5 to 300 bar and at a temperature of from 50 to 200° C., and separating the aqueous phase and the organic phase.
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- First Selective Reduction of Aromatic Nitro Compounds Using Water Soluble Catalysts
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A new methodology has been developed which involves the reduction of substituted nitro aromatics to substituted anilines using a two phase system with water - soluble palladium catalysts.The nitro group was reduced selectively to an amine in up to 85percent yield whereby other functional groups i.e., ketone, nitrile, chloride and alkene were untouched.
- Tafesh, Ahmed M.,Beller, Matthias
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p. 9305 - 9308
(2007/10/02)
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- 3-Cyano-oxanilic acid derivatives
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It has now been discovered that compounds of FIG. 1 STR1 are useful in the prophylactic treatment of sensitized humans and animals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature. The compounds are formulated with pharmaceutical carriers for oral, parenteral, inhalation, or rectal means of administration. Certain compounds are novel.
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- Azo pigments derived from 2-hydroxy-3-carboxynaphthalene containing a substituted or unsubstituted phthalimide
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Azo pigments derived from 2-hydroxy-3-carboxy-naphthalene and containing a substituted or unsubstituted phthalimide radical. The majority give red colorations and due to their excellent fastness properties are particularly valuable for use in surface coatings and resins.
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