- A facile one-pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin- 4-ones
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One pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones by the reaction of 5-amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl3 has been developed. The structures of all the title compounds have been confirmed by IR, 1H-NMR, 13C-NMR, and elemental analyses. Moreover, the structures of one of these compounds, 2c, was confirmed by single-crystal X-ray diffraction.
- Zhang, Xiaohong,Lin, Qiulian,Zhong, Ping
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experimental part
p. 3079 - 3086
(2010/09/04)
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