cas 5351-51-9, 4,5-Dimethyl-thiazole-2-thiol | Articles data ｜lookchem

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5351-51-9

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CARBACEPHEM β-LACTAM ANTIBIOTICS
Carbacephem -lactam antibiotics having structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar1, Ar2, R1 and R2 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.
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Page/Page column 71

(2010/04/06)

CARBACEPHEM β-LACTAM ANTIBIOTICS
Carbacephem β-lactam antibiotics having the following chemical structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar2, R1, R2 and R3 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.
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Page/Page column 85-86

(2009/05/30)

Studies on acetylenic compounds. XXV. Ring closure. (5). New synthetic method of heterocyclic compounds from alpha-amino- and alpha-N-substituted amino- acetylenic compounds.
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YURA
p. 1087 - 1093
(2007/10/04)

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Chemical Properties

Melting Point: 166 °C
Boiling Point: 214.5 °C at 760 mmHg
Flash Point:83.5 °C
Density: 1.28g/cm³
Refractive Index: 1.649
PKA: 8.68±0.60(Predicted)
PSA: 79.93000
LogP: 2.04860

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