α-Alkoxystannanes as masked oxonium ions: application to the synthesis of furo[2,3-b]pyrans
α-Alkoxystannanes undergo oxidation upon treatment with cerium ammonium nitrate generating oxonium ions, which can be trapped in an intramolecular fashion affording furo[2,3-b]pyrans.
Attwood, Michael R.,Gilbert, Philip S.,Lewis, Mark L.,Mills, Keith,Quayle, Peter,Thompson, Simon P.,Wang, Shouming
New strategy for the diastereoselective synthesis of bicyclic 'pre- activated' analogues of cyclophosphamide
The diastereoselective synthesis of 'pro-activated' analogues of cyclophosphamide in the 3-[bis(2-chloroethyl)amino]-2-aza-4,9-dioxa-3- phosphabicyclo(4.3.0)nonane 3-oxide series is described, using either the phosphorylation of an azidoalcohol followed by a reductive cyclisation or the phosphorylation of an acetal alcohol followed by an unprecedent direct Lewis acid catalyzed intramolecular substitution.
Maynard-Faure,Gonser,Vaime,Bouchu
p. 2315 - 2318
(2007/10/03)
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