- Synthesis, inhibition and binding of simple non-nitrogen inhibitors of monoamine transporters
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A series of simple truncated analogues of phenyl tropanes, 2-arylcycloalk-1-enyl carboxylic acid methylesters, were prepared and investigated for their activity towards the dopamine, serotonin and norepinephrine transporters. The compounds were prepared f
- Petersen, Mikkel Due,Boye, Soren Valdgard,Nielsen, Erik Holm,Willumsen, Jeanette,Sinning, Steffen,Wiborg, Ove,Bols, Mikael
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p. 4159 - 4174
(2008/03/12)
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- Tricyclic indanyls as integrin inhibitors
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The present invention is directed to substituted indanyl compounds of Formula (I): Useful for treating integrin-mediated disorders such as, but not limited to unstable angina, thromboemboic disorders, osteoporosis, growth and metastasis of malignant tumors, diabetic retinopathy, arthritis, viral disease and surgical adhesions.
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Page/Page column 18
(2010/02/10)
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