- Triazole antifungal agents
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The invention provides antifungal agents of the formula: STR1 and their pharmaceutically acceptable salts, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and CF3 ; R1 is C1 -C4 alkyl; R2 is H or C1 -C4 alkyl; and "Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C1 -C4 alkyl, C1 -C4 alkoxy, halo, CF3, CN, NO2, NH2, --NH(C1 -C4 alkanoyl) or --NHCO2 (C1 -C4 alkyl).
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