Synthesis and structure activity relationship of guanidines as NPY Y5 antagonists
A series of bis-aryl substituted guanidines have been discovered as potent NPY Y5 antagonists. The SAR and in vitro metabolic stability of these compounds are discussed.
Aquino, Christopher J.,Ramanjulu, Joshi M.,Heyer, Dennis,Daniels, Alejandro J.,Palazzo, Fabio,Dezube, Milana
p. 2691 - 2708
(2007/10/03)
Reaction of biguanides and related compounds. VIII. The condensation of arylbiguanides and N amidino O alkylisoureas with diketene and ethyl acetoacetate
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Furukawa,Yoshida,Goto,Hayashi
p. 2594 - 2601
(2007/10/05)
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