Synthesis of [3-[2-(dimethylamino)ethyl]-2-[[3-(dimethylamino)ethyl]-1H-indol-5-yl] methyl]-1H-indol-5-yl]-N-methylmethanesulfonamide - The main sumatriptane impurity
Alkylation of sumatriptane in position 2 by 3-[2-(dimethylamino)ethyl]-5-indolemethanol has been described. Alternative multistep synthesis of 3-[2-(dimethylamino)ethyl]-5-indolemethanol has been presented.
Skwierawska,Paluszkiewicz
p. 329 - 332
(2007/10/03)
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Get Best Price for545338-89-4[3-[2-(diMethylaMino)ethyl]-2-[[3-[2-(diMethylaMino)ethyl]-1H-indol-5-yl]Methyl]-1H-indol-5-yl]-N-MethylMethanesulfonaMide, succinate salt