Copper powder-catalyzed N-arylation of imidazoles in water using 2-(hydrazinecarbonyl)pyridine N-oxides as the new ligands
2-(2-Hydrazinecarbonyl)pyridine N-oxides, which were derived from pyrrole-2-carbohydrazides and pyridine N-oxides, were synthesized and utilized as the ligands for copper powder-catalyzed N-arylation of imidazoles with aryl halides in water. Imidazoles could be arylated smoothly with various aryl halides to provide the title products in preferable yields without the need of an inert atmosphere.
Wu, Feng-Tian,Yan, Nan-Nan,Liu, Ping,Xie, Jian-Wei,Liu, Yan,Dai, Bin
p. 3249 - 3251
(2014/06/09)
Synthesis of N-(Carbonylamino)-1,2,3,6-tetrahydropyridines with Analgesic, Antiinflammatory, and Hyperglycemic Activity
A group of N-(carbonylamino)-1,2,3,6-tetrahydropyridines was synthesized to investigate the effects that changes in functionality at the carbonyl group have on analgesic, antiinflammatory, and hyperglycemic activities.One of the most active analgesic comp
Yeung, Jupita M.,Corleto, Linda A.,Knaus, Edward E.
p. 191 - 195
(2007/10/02)
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