Thiabenzazonium, a new 1,5 benzodiazepine derivative with antimicrobial activity
The synthesis, physicochemical properties and antimicrobial activity of tibezonium iodide (thiabenzonium), a new quaternary ammonium derivative of 1,5 benzodiazepine, are described. Tibezonium iodide has high bacteriostatic and bactericidal activity against some gram positive bacteria which are agents of oropharyngeal infections.