Reactions of methotrexate with hypobromous acid and hypochlorous acid
Methotrexate is a folate antagonist cytotoxic drug employed in the therapy of cancers and rheumatoid arthritis. Hypobromous acid (HOBr) and hypochlorous acid (HOCl) are generated by eosinophils and neutrophils at inflammation sites. The administered metho
Suzuki, Toshinori,Takeuchi, Rie
p. 1250 - 1254
(2019/11/16)
Aromatic Chlorination of p-Aminobenzoic Acid Derivatives. Improved Syntheses of Mono- and Dichloromethotrexate
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Martinelli, Jack E.,Chaykovsky, Michael
p. 527 - 529
(2007/10/02)
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