- PHARMACEUTICAL COMPOSITIONS AND METHODS OF PREVENTING, TREATING, OR INHIBITING INFLAMMATORY DISEASES, DISORDERS, OR CONDITIONS OF THE SKIN, AND DISEASES, DISORDERS, OR CONDITIONS ASSOCIATED WITH COLLAGEN DEPLETION
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The present invention provides compositions and methods for preventing, treating, or inhibiting inflammatory diseases, disorders, or conditions of the skin, and diseases, disorders, or conditions associated with collagen depletion using one or more estrogenic agents.
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- 7-Substituted 2-phenyl-benzofurans as ERβ selective ligands
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Substituted benzofuran 21 is a potent and selective ER ligand. A series of 2-(4-hydroxy-phenyl)-benzofuran-5-ols with relatively lipophilic groups in the 7-position of the benzofuran was prepared and the affinity and selectivity for ERβ was measured. Many
- Collini, Michael D.,Kaufman, David H.,Manas, Eric S.,Harris, Heather A.,Henderson, Ruth A.,Xu, Zhang B.,Unwalla, Rayomand J.,Miller, Chris P.
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p. 4925 - 4929
(2007/10/03)
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- Substituted 2-phenyl benzofurans as estrogenic agents
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This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.
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