- Selective Monoarylation of Aromatic Ketones and Esters via Cleavage of Aromatic Carbon-Heteroatom Bonds by Trialkylphosphine Ruthenium Catalysts
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We report here the ruthenium-catalyzed selective monoarylation of aromatic ketones bearing two ortho carbon-heteroatom (O or N) bonds. Under the newly developed catalyst system consisting of RuHCl(CO)(PiPr3)2, CsF, and sty
- Kondo, Hikaru,Kochi, Takuya,Kakiuchi, Fumitoshi
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supporting information
p. 794 - 797
(2017/03/01)
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- PH-Responsive N-heterocyclic carbene copper(i) complexes: Syntheses and recoverable applications in the carboxylation of arylboronic esters and benzoxazole with carbon dioxide
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A pH-controlled monophasic/biphasic switchable system has been developed as a green and novel strategy for homogeneous catalyst recycling, which has been successfully applied to the Cu-NHC-catalyzed carboxylation of organoboronic esters and benzoxazole with carbon dioxide. Additionally, the present strategy could also be extended to the Ag-NHC-catalyzed carboxylation of terminal alkyne. The tertiary amine-functionalized catalysts could be used for at least four times with a slight loss of activity.
- Wang, Wenlong,Zhang, Guodong,Lang, Rui,Xia, Chungu,Li, Fuwei
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supporting information
p. 635 - 640
(2013/03/29)
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- Copper-catalyzed amination of arylboronates with N,N-dialkylhydroxylamines
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A tolerant coupling: The title reaction has been developed to deliver arylamines (see scheme; Bz=benzoyl, dppbz=1,2-bis(diphenylphosphino)benzene). The catalysis is based on electrophilic, umpolung amination and enables the use of secondary acyclic amines. Various functional groups are tolerated, thus opening up a new substrate class for the Chan-Lam-type coupling.
- Matsuda, Naoki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
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supporting information; body text
p. 3642 - 3645
(2012/05/20)
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- Copper-catalyzed cross-coupling reaction of organoboron compounds with primary alkyl halides and pseudohalides
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Non-activated alkyl electrophiles, including alkyl iodides, bromides, tosylates, mesylates, and even chlorides, underwent copper-catalyzed cross-coupling with aryl boron compounds and alkyl 9-BBN reagents (see scheme; 9-BBN=9-borabicyclo[3.3.1]nonane). The reactions proceed with practically useful reactivities and thus complement palladium- and nickel-catalyzed Suzuki-Miyaura coupling reactions of alkyl halides.
- Yang, Chu-Ting,Zhang, Zhen-Qi,Liu, Yu-Chen,Liu, Lei
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supporting information; experimental part
p. 3904 - 3907
(2011/05/15)
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- HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS
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The invention relates to chemical compounds of formula (IB): or a salt thereof. In some embodiments, the invention relates to inhibitors of UDP-3-0 — (R-S-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC). In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein and their use in the prevention and/or treatment of Gram- negative bacterial infections.
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Page/Page column 48
(2010/09/18)
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- Carboxylation of organoboronic esters catalyzed by N-heterocyclic carbene copper(I) complexes
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Copper complexes with a CO2 fixation: Copper(I) complexes serve as excellent catalysts for the carboxylation of aryl- and alkenylboronic esters with CO2, affording a variety of functionalized carboxylic acid derivatives (see scheme). Important active intermediates such as the copper(I) aryl and carboxylate complexes, [(IPr)CuR] and [(IPr)CuOCOR] (R = 4-MeOC 6H4, IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2- ylidene), are isolated and structurally characterized. (Chemical Equation Presented).
- Ohishi, Takeshi,Nishiura, Masayoshi,Hou, Zhaomin
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supporting information; experimental part
p. 5792 - 5795
(2009/03/11)
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- Copper(I)-catalyzed carboxylation of aryl- and alkenylboronic esters
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(Chemical Equation Presented) The copper(I)-catalyzed carboxylation reaction of aryl- and alkenylboronic esters proceeded smoothly under CO 2 to give the corresponding carboxylic acid in good yield. This reaction showed wide generality with higher functional group tolerance compared to the corresponding Rh(I)-catalyzed reaction.
- Takaya, Jun,Tadami, Satoshi,Ukai, Kazutoshi,Iwasawa, Nobuharu
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supporting information; experimental part
p. 2697 - 2700
(2009/05/26)
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