- INTERMEDIATES FOR THE SYNTHESIS OF BENZIMIDAZOLE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF
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This invention provides a process for the preparation of a benzimidazole derivative (I) or a pharmaceutically acceptable salt thereof,wherein R1is C1-C6alkyl, C1-C6alkoxyl, etc., R2is C1-C6alkyl, and R3is hydrogen or a protecting group, which exhibits excellent hypoglycemic action, said process comprising condensation of an amine derivative (III) with a carboxylic acid derivatives (II) to afford a compound (IV), followed by cyclization of compound (IV) in the presence of an acid.
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