- On the influence of unsaturation on the macrolactonization of hydroxy fatty acids
-
Regioselectivity and yields of Yamaguchi cyclization of (15S, 16S)-15, 16-dihydroxy-otadecyl-(6Z, 9Z, 12Z)-trienoic acid and its saturated homologue have been compared at different temperatures and concentrations. For the unsaturated species the regiosele
- Caruso, Tonino,Donnamaria, Carmen,Artillo, Antonietta,Peluso, Andrea,Spinella, Aldo,Monaco, Guglielmo
-
-
Read Online
- Facile determination of the absolute stereochemistry of hydroxy fatty acids by GC: application to the analysis of fatty acid oxidation by a P450BM3 mutant
-
The determination of the absolute stereochemistry of hydroxy fatty acid methyl esters as their (S)-ibuprofen esters is possible via standard gas chromatographic techniques. Analyses of various racemic and nonracemic standards and mixtures from enzymic oxi
- Cryle, Max J.,De Voss, James J.
-
p. 547 - 551
(2007/10/03)
-
- Products of cytochrome P450Biol (CYP107H1)-catalyzed oxidation of fatty acids
-
(Matrix presented) Oxidation of tetradecanoic and hexadecanoic acids by cytochrome P450Biol (CYP107H1) produces mainly the 11-, 12-, and 13-hydroxy C14 fatty acids and the 11- to 15-hydroxy C16 fatty acids, respectively. In contrast to previous reports, terminal hydroxylation is not observed. The enantiospecificity of fatty acid hydroxylation by P450Biol was also determined, and the enzyme was shown to be moderately selective for production of the (R)-alcohols.
- Cryle, Max J.,Matovic, Nick J.,de Voss, James J.
-
p. 3341 - 3344
(2007/10/03)
-