Tetrakisphosphates and Bispyrophosphates of myo-Inositol Derivatives as Allosteric Effectors of Human Hemoglobin: Synthesis, Molecular Recognition, and Oxygen Release
Various 2,5- and 1,4-substituted and unsubstituted myo-inositol tetrakisphosphates and bispyrophosphates were prepared following a general synthetic pathway. All final compounds were tested for their capability to induce oxygen release from human hemoglob
Koumbis, Alexandros E.,Duarte, Carolina D.,Nicolau, Claude,Lehn, Jean-Marie
p. 169 - 180
(2013/01/09)
Stereospecific synthesis of 1,4-di-O-methyl-myo-inositol (liriodendritol)
1,4-di-O-methyl-myo-inositol, a natural product, was synthesised starting from p-benzoquinone. The treatment of 5,6-dibromocyclohex-2-ene-1,4-diol with Na/ROH-system afforded a C2-symmetric conduritol-B derivative key intermediate followed by a
Kelebekli, Latif
p. 626 - 628
(2008/09/19)
Efficient synthetic routes to fluorinated isosteres of inositol and their effects on cellular growth
Efficient synthetic routes to several fluorinated isosteres of inositol have been developed that are based upon the unexpected selectivity observed in the (diethylamido)sulfur trifluoride reaction of polyhydroxylated cyclohexane derivatives. The conversio
Kozikowski, Alan P.,Fauq, Abdul H.,Powis, Garth,Melder, Deborah C.
p. 4528 - 4531
(2007/10/02)
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