Rigidified multivalent lactose molecules and their interactions with mammalian galectins: A route to selective inhibitors
New and rigid multivalent lactose molecules were prepared. The structures contain lactose-2-aminothiazoline units at the periphery that were formed from a cyclisation of the thiourea sulphur onto the triple bond of the spacer. The lactosides were evaluate
Vrasidas, Ioannis,Andre, Sabine,Valentini, Paola,Boeck, Corina,Lensch, Martin,Kaltner, Herbert,Liskamp, Rob M.J.,Gabius, Hans-J.,Pieters, Roland J.
p. 803 - 810
(2007/10/03)
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