The present invention relates to a compound of formula (I): or a pharmaceutical acid addition salt thereof; which is useful for activating 5-HT1freceptors and inhibiting protein extravasation in a mammal.
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(2008/06/13)
Aromatic ethers derived from indoles which are useful as medicaments
The present invention relates to new aromatic ethers derived from indole and having general formula (I) as well as to their preparation methods, pharmaceutical compositions containing them and their utilization as a medicament for the treatment of disease
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(2008/06/13)
Synthesis and Structure-Activity Relationships of 5-Substituted Tryptamine Derivatives of o-Tolylpiperazine as Agonists at 5-HT1D Receptors
Analogs of 1-[2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-acetyl]-4-[o-tolyl]-piperazide 1, recently reported as a novel potent 5HT1D agonist, have been prepared and tested as 5HT1A, 5HD1Dα and 5HT1Dβ ligands and eva
Perez, M.,Pauwels, P. J.,Palmier, C.,John, G. W.,Valentin, J. P.,Halazy, S.
p. 680 - 689
(2007/10/03)
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