cas 575-85-9, 6-FLUOROTRYPTAMINE | Articles data ｜lookchem

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575-85-9

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Process for the Manufacture of Idalopirdine via Hydrogenation of an Imine
The present invention relates to the preparation of N-(2-(6-fluoro-1H-indol-3-yl)-ethyl)-3-(2,2,3,3-tetrafluoropropoxy)-benzylamine (Compound I), INN-name idalopirdine, and pharmaceutically acceptable salts thereof:
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Paragraph 0127

(2017/10/27)

PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE
Disclosed herein is a process for the preparation of idalopirdine and pharmaceutically acceptable salts thereof.
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Page/Page column 0089

(2016/07/05)

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Chemical Properties

Melting Point: 81-83 °C
Boiling Point: 346 °C at 760 mmHg
Flash Point:163 °C
Density: 1.249 g/cm³
Solubility:DMSO (Slightly), Methanol (Slightly)
Storage Temp.:−20°C
Vapor Pressure: 5.95E-05mmHg at 25°C
Refractive Index: 1.643
PKA: 16.60±0.30(Predicted)
Sensitive: Light Sensitive
PSA: 41.81000
LogP: 2.50850

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