Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT 2C receptor
Evaluation of selected compounds from our Corporate Compound Library in a human 5-HT2C receptor binding assay led to the discovery of WAY-629, a cyclohexyl[b][1,4]benzodiazepinoindole (Ki 56nM, Emax 90%), which is selectiv
Sabb, Annmarie L.,Vogel, Robert L.,Welmaker, Gregory S.,Sabalski, Joan E.,Coupet, Joseph,Dunlop, John,Rosenzweig-Lipson, Sharon,Harrison, Boyd
p. 2603 - 2607
(2007/10/03)
[1,4]Diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
Compounds of Formula I or a pharmaceutically acceptable salt thereof are provided: where R1 through R7 are defined herein. The compounds of Formula I are 5HT2c agonists or partial agonists, and are useful for treating a variety of di
-
Page/Page column 15
(2008/06/13)
More Articles about upstream products of 57756-37-3