- THE INCORPORATION OF ORNITHINE-2> INTO NICOTINE AND NORNICOTINE ESTABLISHED BY NMR
-
DL-Ornithine-2> was synthesized from acetate- and ethyl acetamidocyanoacetate.This labelled material was mixed with DL-ornithine- and fed to Nicotiana glutinosa plants by the wick method.After 10 days the plants were harvested affording radioactive nicotine and nornicotine (0.14percent and 0.051percent specific incorporations, respectively).Even at these low specific incorporations an examination of their 13C NMR spectra established the incorporation of ornithine symmetrically into the pyrrolidine rings of these alkaloids.Satellites were observable at the signals due to C-2'. 3', 4' and 5' positions, arising by the presence of contiguous carbons at C-2', 3' and C-4', 5'. - Key Word Index: Nicotiana glutinosa; Solanaceae; nicotine; nornicotine; ornithine; 13C NMR spectroscopy; biosynthesis.
- Leete, Edward,Yu, Ming-Li
-
-
Read Online
- Generation of [β-(phenylsulfonyl)alkylidene]carbenes from hypervalent alkenyl- and alkynyliodonium tetrafluoroborates and synthesis of 1-(phenylsulfonyl)cyclopentenes
-
Michael-type addition of benzenesulfinic acid to alkynyl(phenyl)iodonium tetrafluoroborates in methanol gives stereoselectively (Z)-(β-(phenylsulfonyl)alkenyl)iodonium tetrafluoroborates in high yields. [β-(Phenylsulfonyl)alkylidene]carbenes derived from
- Ochiai, Masahito,Kunishima, Munetaka,Tani, Shohei,Nagao, Yoshimitsu
-
p. 3135 - 3142
(2007/10/02)
-
- Transacylation of Cephalosporin; Isolation and Reactions of the Imidate Esters
-
The reaction of the imidate ester of methyl 7-acetamidoceph-3-em-4-carboxylate (2) and phenylacetyl chloride was followed by 13C n.m.r. spectroscopy, which disclosed the intermediacy of the adduct of (2) with the acyl chloride.Transacylations of methyl 7-
- Saito, Toshinori,Nishihata, ken,Fukatsu, Syunzo
-
p. 1058 - 1063
(2007/10/02)
-