Kinetic resolution of heteroaryl β-hydroxy sulfides catalyzed by Humicola lanuginosa lipase
Humicola lanuginosa lipase-catalyzed resolution of heteroaryl substituted β-hydroxy sulfides by irreversible transesterification using vinyl acetate as acylating agent is discussed. The ee of the resolved alcohols was determined from the 1H NMR of their corresponding (S)-(+)-O-acetylmandelic acid esters.