Multisignal labeling reagents and processes and uses therefor
Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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Page/Page column 35
(2015/11/09)
Potential antitumor agents. 44. Synthesis and antitumor activity of new classes of diacridines: Importance of linker chain rigidity for DNA binding kinetics and biological activity
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Denny,Atwell,Baguley,Wakelin
p. 1568 - 1574
(2007/10/02)
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