- Rho-kinase inhibitors
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Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
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Page/Page column 76
(2010/02/05)
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- A Convenient Synthesis of the Thienopyridine Nucleus
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The unsubstituted thienopyridine ring system was prepared from thiophene-3-carboxaldehyde in 4 steps. The sequence is suitable for scale-up.
- Wikel, James H.,Denney, Michael L.,Vasileff, Robert T.
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p. 289 - 290
(2007/10/02)
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