- RAD51 INHIBITORS
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This application is directed to inhibitors of RAD51 represented by the following structural formula, (I), and methods for their use, such as to treat cancer, autoimmune diseases, immune deficiencies, or neurodegenerative diseases.
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Page/Page column 221-222
(2020/09/27)
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- SPIROCHROMANONE DERIVATIVES AS ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS
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The invention relates to a compound of a formula (I): , or a pharmaceutically acceptable salt or ester thereof, useful as a therapeutic agent for various ACC-related disorders.
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Page/Page column 105
(2008/06/13)
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- Synthesis and hypolipidemic activity of N-substituted phthalimides. Part V
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A series of N-aryl- or N-(1,2,4-triazol-yl)-phthalimides (4a-4i) have been synthesized starting from phthalic anhydride (1) and an appropriate amine (2a-2i). All compounds presented hypolipidemic activity, but compound 4d proved to be the most active and reduced plasma cholesterol and triglyceride levels in Swiss white mice significantly.
- Sena, Vera L.M.,Srivastava, Rajendra M.,Silva, Ricardo O.,Lima, Vera L.M.
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p. 1283 - 1288
(2007/10/03)
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- Synthesis and antibacterial activities of some 1,2,4-triazole derivatives
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Reactrions of 3-amino-1,2,4-triazole with some dicarboxylic acid anhydrides and diketones were studied. The structural assignments of the compounds obtained from the reactions are based on elemental analyses and spectral data. The compounds were screened for their in vitro antibacterial activities.
- Ikizler, Aykut A.,Johansson,Bekircan,Celik
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p. 283 - 288
(2007/10/03)
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