Compounds of Formula I that inhibit microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (Apo B) secretion and their uses in the treatment of diseases linked thereto in animals are described herein.
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Page/Page column 69
(2011/12/04)
Benzisoxazole-derived antidiabetic compounds
The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
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(2008/06/13)
Antidiabetic agents
The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
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(2008/06/13)
Pyrazol-1-ylphenylacetic acids
Pyrazol-1-ylphenylacetic acids of the formula STR1 wherein R1, R2 and R3 are the same or different and denote a hydrogen atom or a halogen atom, R4 denotes a hydrogen atom or an alkyl group, A B denotes a carbon-carbon single or double bond, and their salts are pharmacologically active and are useful as medicaments. Medicament compositions are produced therefrom. Their functional carboxylic acid derivatives and other new intermediates are used in their preparation.
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(2008/06/13)
Hydroxyalkylenimino-phenyl-acetic acids
New α-(cyclic tert. aminophenyl)-aliphatic acids, e.g. those of the formula SPC1 R1 = h or alkyl R2 = h, alk(en)yl, cycloalk(en)- yl or cycloalk(en)yl-alkyl A = hydroxylated lower alkylene And functional derivatives thereof, are anti-inflammatory agents.
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(2008/06/13)
Tertiary aminoacids as anti-inflammatory agents
New α-(cyclic tert. aminophenyl)-aliphatic acids, e.g. those of the formula SPC1 R1 = h or alkyl R2 = h, alk(en)yl, cycloalk(en)yl or cycloalk(en)yl-alkyl A = hydroxylated lower alkylene And functional derivatives thereof, are anti-inflammatory agents.
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(2008/06/13)
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