- Green synthesis method of 2-hydroxy-5-nonyl acetophenone oxime
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The invention provides a green synthesis method of 2-hydroxy-5-nonyl acetophenone oxime. The green synthesis method comprises the following steps: preparing nonyl phenol ethyl ester from 4-nonyl phenol and acetic acid; diluting the obtained nonyl phenol ethyl ester with n-hexane, adding a solid composite catalyst formed by silica gel loaded composite chlorine salt, uniformly mixing, and carrying out rearrangement reaction under microwave treatment to generate 2-hydroxy-5-nonyl acetophenone; and carrying out oximation reaction on the generated 2-hydroxy 5-nonyl acetophenone to generate 2-hydroxy 5-nonyl acetophenone oxime. According to the method disclosed by the invention, the solid composite catalyst and microwave-assisted treatment are utilized, so that the defects that a large amount ofaluminum-containing waste is generated by post-treatment, equipment is corroded and the like in the existing process are overcome, the green degree of the process is remarkably improved, and industrial promotion is facilitated.
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- Ketoximes, processes therefor, and copper extraction process
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Ketoximes, processes for their preparation, compositions containing them, and a copper extraction process using the compositions. One process for the preparation of the ketoximes comprises the following steps: A) reacting a phenol with a monocarboxylic acid, monocarboxylic acid halide, or monocarboxylic acid anhydride in an inert organic solvent in the presence of an acid catalyst to esterify the phenol; B) removing any water of reaction produced in step A) either during step A) or in a separate step following step A); C) adding a Lewis acid to the resulting anhydrous reaction mixture; D) heating the reaction mixture from step C) to a reaction temperature sufficient to obtain a ketone by the Fries Rearrangement; E) maintaining the heated reaction mixture for a time period of from 2 to 8 hours at the reaction temperature; F) at a time of from half to three-quarters of said time period, adding to the heated reaction mixture additional aliphatic monocarboxylic acid, acid halide, or acid anhydride, optionally with additional Lewis acid, and continuing to maintain the heated reaction mixture at the reaction temperature for the remainder of said time period; G) isolating the ketone reaction product from the reaction mixture; and H) reacting hydroxylamine or a salt thereof with the ketone obtained in step G) to produce a ketoxime from said ketone.
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Page column 11-12
(2008/06/13)
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