The invention provides an antidepressant composition which comprises, as an active ingredient, a pyroglutamide derivative of the general formula [I]: STR1 wherein Y is CH 2 or N--R (in which R is an alkoxycarbonyl group, a substituted or unsubstituted aralkyl group or a morpholinocarbonylalkyl group), or a pharmaceutically acceptable salt thereof. The compound of the invention is useful in the prevention or treatment of depressive state or depression.
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(2008/06/13)
Pyroglutamide derivatives
Pyroglutamide derivatives have been found to be useful as nootropic agents for administration to humans and animals.