- New routes to 1,4-benzodiazepin-2,5-diones
-
1,4-benzodiazepin-2,5-diones have been synthesized in good overall yields by two routes, the first one by cyclisation of dipeptides prepared from Boc anthranilic acid and α-amino acid methyl esters, the second one by reaction of N-carboxy α-amino acid anhydrides with Boc anthranilic acid.
- Akssira,Boumzebra,Kasmi,Dahdouh,Roumestant,Viallefont
-
p. 9051 - 9060
(2007/10/02)
-
- New synthesis of 1,4 benzodiazepine-2,5-diones by means of HCl gas catalyst
-
A new synthesis of 1,4-benzodiazepinediones 4, particularly 1,4-dihydro1H-1,4-benzodiazepine-2,5-dione, 4c key intermediate of metabolites cyclopenin 9, cyclopenol 10, cyclopeptine 11 and dehydrocyclopeptide 12, was achieved by action of dry HCl gas in DM
- Akssira,Boumzebra,Kasmi,Dahdouh,Roumestant,Viallefont
-
p. 2265 - 2272
(2007/10/02)
-
- A Versatile Synthesis of 3H-1(H),4(H)-Benzodiazepin-2,5-diones
-
Reaction of isatoic anhydrides (1) and α-amino acids (2) in glacial acetic acid under reflux gave 3H-1(H),4(H)-benzodiazepin-2,5-diones (3) in good yields.These compounds have been characterised by UV, IR, mass, PMR and 13C-NMR spectra.
- Mohiuddin, G.,Reddy, P. S. N.,Ahmed, Khalil,Ratnam, C. V.
-
p. 905 - 907
(2007/10/02)
-