A New, General, and Convenient Synthesis of 5-Deazaflavins (5-Deazaisoalloxazines) and Bis-(5-deazaflavin-10-yl)alkanes
The condensation of 6-substituted aminouracils or bis(uracil-6-amino)alkanes with o-halogenobenzaldehydes in dimethylformamide led to the formation of the corresponding 5-deazaflavins or bid(5-deazaflavin-10-yl)alkanes in a single step.
A New, General, and Convenient Synthesis of 5-Deazaflavins (5-Deazaisoallooxazines)
The condensation of 6-substituted-aminouracils with o-halogenobenzaldehydes in dimethylformamide led to the formation of the corresponding 5-deazaflavins in a single step.
A Novel Synthesis of Pyrimidoquinoline-2(3H),4(10H)-diones (5-Deazaflavins) and Analogues by the Oxidative Cyclization of 5,5'-Arylmethylenebis-(6-alkylamino-3-methyluracils)
The oxidative coupling of 5,5'-arylmethylenebis-(6-alkylamino-3-methyluracils), prepared by the condensation of 6-alkylamino-3-methyluracils and arenecarbaldehydes, with diethyl azodiformate afforded the corresponding pyrimidoquinoline-2(3H),4(10H)