- Electrochemical Aziridination by Alkene Activation Using a Sulfamate as the Nitrogen Source
-
The first direct aziridination of triaryl-substituted alkenes was achieved by means of an electrochemical process that could extend to multisubstituted styrenes. Specifically, hexafluoroisopropanol sulfamate was used as a nucleophilic nitrogen source. Mechanistic experiments suggest that this electrochemical process proceeds by stepwise formation of two C?N bonds through reactions between cationic carbon species and the sulfamate.
- Li, Jin,Huang, Wenhao,Chen, Jingzhi,He, Lingfeng,Cheng, Xu,Li, Guigen
-
supporting information
p. 5695 - 5698
(2018/04/30)
-
- 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME
-
A compound represented by the formula: wherein R1 represents a hydrogen atom, a halogen atom, alkyl group, etc., ???R2 represents a hydrogen atom, a halogen atom, alkyl group, etc., ???R3, R4, R5, R6 and R7 each independently represent a hydrogen atom, a halogen atom, a substitutable alkyl group, a substitutable alkenyl group, alkynyl group, a substitute-able cycloalkyl group, etc., or adjacent two of R3, R4, R5, R6 and R7 may together with the carbon atoms to which the respective substituents are bonded form a ring which may be substituted, ???m and n each independently represent 0 or 1, a salt thereof or an ester derivative thereof; an agricultural chemical containing the same as an active ingredient; and a herbicidal composition containing the compound and a second herbicidally active compound as active ingredients.
- -
-
-
- Proteomimetic compounds and methods
-
The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
- -
-
-
- Synthesis of polysubstituted alkenes by Heck vinylation or Suzuki cross-coupling reactions in the presence of a tetraphosphane-palladium catalyst
-
Through the use of [PdCl(C3H5)]2/cis,cis,cis-1,2,3, 4-tetrakis[(diphenylphosphanyl)methyl]cyclopentane as a catalyst, a range of vinyl bromides undergo Suzuki cross-couplings with arylboronic acids in good yields. Furthermore, the catalyst can be used at low loadings, even for reactions of sterically hindered substrates. Mediated by this catalyst, stilbene and 1,1-diphenylethylene undergo Heck reactions with aryl halides to give triarylethylene derivatives. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
- Berthiol, Florian,Doucet, Henri,Santelli, Maurice
-
p. 1091 - 1096
(2007/10/03)
-