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604-33-1

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Enzymatic synthesis of steryl esters of polyunsaturated fatty acids
Steryl esters of long-chain fatty acids have water-holding properties, and polyunsaturated fatty acids (PUFA) have various physiological functions. Because steryl ester of PUFA can be expected to have both features, we attempted to synthesize steryl esters of PUFA by enzymatic methods. Among lipases used, Pseudomonas lipase was the most effective for the synthesis of cholesteryl docosahexaenoate. When a mixture of cholesterol/docosahexaenoic acid (3:1, mol/mol), 30% water, and 3000 units/g of lipase was stirred at 40 °C for 24 h, the esterification extent attained 89.5%. Under the same reaction conditions, cholesterol, cholestanol, and sitosterol were also esterified efficiently with docosahexaenoic, eicosapentaenoic, arachidonic, and γ-linolenic acids.
Shimada, Yuji,Hirota, Yoshinori,Baba, Takashi,Sugihara, Akio,Moriyama, Shigeru,Tominaga, Yoshio,Terai, Tadamasa
p. 713 - 716
(1999)
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PKC activators and combinations thereof
The present disclosure relates to PKC activators and combinations thereof. The disclosure further relates to compositions, kits, uses, and methods thereof.
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Page/Page column 46

(2020/11/13)

ESTERS OF DCPLA AND METHODS OF TREATMENT USING THE SAME
The present disclosure relates to esters of 8-[2-(2-pentyl- cyclopropylmethyl)cyclopropyl]-octanoic acid ("DCPLA"). The disclosure further relates to compositions, kits, and methods for treatment using the esters.
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Paragraph 0112

(2013/05/23)

PKC ACTIVATORS AND COMBINATIONS THEREOF
The present disclosure relates to PKC activators and combinations thereof. The disclosure further relates to compositions, kits, uses, and methods thereof.
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Paragraph 0211

(2013/05/23)

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Chemical Properties

Appearance/Colour :White powder.
Melting Point: 41-42.5 °C
Boiling Point: 677.3±44.0 °C(Predicted)
Flash Point:113 °C
Density: 0.96±0.1 g/cm3(Predicted)
Storage Temp.:−20°C
PSA: 26.30000
LogP: 13.75310

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